Mark Wahlberg as John Bennett
Seth MacFarlane as Ted
Mila Kunis as Lori Collins, John’s girlfriend
Joel McHale as Rex, Lori’s manager and John’s nemesis
Giovanni Ribisi as Donny, Ted’s biggest fan and adversary
Aedin Mincks as Robert, Donny’s son
Patrick Warburton as Guy, John’s co-worker
Laura Vandervoort as Tanya, John’s co-worker
Matt Walsh as Thomas Murphy, John’s boss
Jessica Barth as Tami-Lynn McCafferty, Ted’s girlfriend and co-worker
Bill Smitrovich as Frank Stevens, Ted’s boss
Alex Borstein as Helen Bennett, John’s mother
Ralph Garman as Steve Bennett, John’s father
Jessica Stroup as Tracy, Lori’s co-worker
Sam J. Jones as himself
Ryan Reynolds as Jared, Guy’s boyfriend
Norah Jones as herself
Tom Skerritt as himself
Mike Henry as a Southern newscaster
Robert Wu as Quan Ming/Ming the Merciless
Ted Danson as himself
Patrick Stewart as Himself (Narrator)
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